Understanding TNF

A researcher and founder of the Institute of Neurological Recovery, Edward Tobinick, MD, focuses on the role of TNF, an immune signaling molecule, in the development of several different illnesses. According to modern scientific papers, high levels of TNF in the brain may inhibit proper neurological function. Interestingly, it is not TNF at normal physiological levels that causes problems, but rather excessive levels of TNF that seem to contribute to chronic brain dysfunction.

Only when TNF levels rise beyond the norm does the brain begin to have trouble operating. Experts began noticing TNF’s role in brain dysfunction first in people with malaria and then later in patients impacted by Alzheimer’s disease. In terms of the latter, a study discovered that individuals with Alzheimer’s had 25 times more TNF than normal in their cerebrospinal fluid. Follow-up research suggests that TNF may be a primary factor in brain dysfunction resulting from a variety of disorders.

For more information about Dr. Edward Tobinick, his research into TNF, and his development of a drug to treat people with high TNF levels, visit Tobinick.com.


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