The Benefits of Off-Label Drug Prescription and Use

Dr. Edward Tobinick, founder of the Institute for Neurological Research, conducted the initial clinical work that found etanercept to be an effective treatment for sciatica and other forms of intervertebral disc-related neuropathic pain. Edward Tobinick has published multiple articles in the medical literature and reviewed research findings as an ad hoc reviewer in leading medical journals, including Brain Research and Experimental Neurology, among others.

When a doctor prescribes a medication for a purpose other than those specifically approved by the Food and Drug Administration (FDA), it is known as off-label drug use. This practice is very common among medical practitioners; 20 percent of outpatient prescriptions in the U.S. are off-label.

Some drugs have multiple beneficial uses. For example, oncologists often prescribe certain off-label drugs to treat different types of cancers. Off-label use is also common in the treatment of heart disease: beta-blockers are FDA approved to combat high blood pressure, but cardiologists often use them to treat heart failure.

Off-label use enables doctors to apply their deep knowledge of the various uses and methods of action of prescription drugs, in some cases resulting in more effective care for patients. Off-label use also allows for clinical innovation and the possibility of important medical discoveries.


Venice Family Clinic Sponsors Annual Art Walk & Auctions

As the founder of the Institute of Neurological Recovery, Dr. Edward Tobinick conducts groundbreaking research to offer alternative treatment options for patients with neurological disorders. Additionally, Dr. Edward Tobinick is a benefactor of the Venice Family Clinic, an organization that provides quality health care to underserved communities in Los Angeles County.

A nonprofit organization, the Venice Family Clinic relies on the support of partner medical centers, physicians, and community members to provide health services to more than 24,000 patients each year. Venice Art Walk & Auctions, the clinic’s largest fundraising event, was established in 1979 by local artists and volunteers. It has become a significant resource for the organization, drawing more than $600,000 in donations in recent years, while also serving as a showcase for the creative community of Venice, California.

In 2014, Venice Family Clinic held its annual fundraising event at the Google headquarters in Venice, celebrating more than 40 years of community health service. The event was open to the public and featured more than 300 original pieces in a silent art auction, in addition to live entertainment and gourmet food trucks. For the first time, the clinic also shared with supporters exactly how their contributions would benefit the community. Bid sheets for the silent auction specified the type of care or equipment, such as infant car seats or diabetes treatment, that could be provided with each bid increment.